G protein-coupled receptor class C group 5 member B pseudogene

The entity "G protein-coupled receptor, family C, group 5, member B pseudogene" (ENSG00000234451) is a pseudogene of the G protein-coupled receptor class C group 5 member B (GPRC5B) gene[1]. Pseudogenes resemble functional genes in sequence but lack the coding potential to produce a functional protein and generally do not contribute to normal biological function or perform roles as classic therapeutic targets[1]. There is no evidence that this pseudogene is transcribed or translated into a functional protein, and it should not be confused with the functional GPRC5B receptor, which has been studied for its physiological and pathophysiological roles in the nervous and immune systems[2][3]. Pseudogenes like ENSG00000234451 typically serve as genomic remnants of gene duplication or retrotransposition events, and are not considered valid drug targets. Key clarification: - ENSG00000234451 is not a protein-coding gene—it is annotated as a pseudogene corresponding to the GPRC5B receptor[1]. - The functional, protein-coding GPRC5B (distinct from this pseudogene) belongs to the class C GPCR family and is implicated in central nervous system and immune function[2][3], but this does not apply to this pseudogene entry. If you are seeking data on the functional GPRC5B receptor (not the pseudogene), please specify, as it is a distinct entity both in function and drug discovery relevance.

Other names

GPRC5B pseudogeneGPRC5B-PS