G protein pathway suppressor 1 pseudogene

G protein pathway suppressor 1 pseudogene (LOC644269, ENSG00000219240) is a human pseudogene related to the G protein pathway suppressor 1 gene. Pseudogenes are non-protein-coding genomic elements that resemble known genes but have lost the ability to encode functional proteins due to disabling mutations[1][2]. While many pseudogenes are transcriptionally silent, some may be transcribed and can regulate gene expression at the RNA level, for example by acting as microRNA decoys or sources of regulatory small RNAs, mechanisms reported in some well-studied pseudogenes[2][8]. However, there is no evidence that LOC644269 is a functional protein nor that it serves as a validated therapeutic target. As a pseudogene, it is not considered a receptor, enzyme, transporter, or druggable target; entries referencing ENSG00000219240 as a druggable entity are likely incorrect or based on confusion with the protein-coding GPS1 gene[1].

Other names

LOC644269ENSG00000219240