Target intelligence / Profile preview

G protein subunit gamma 10 pseudogene 1 (GNG10P1)

Target
GNG10P1
Molecular classification
Other, Pseudogene related to G protein gamma subunits
01

Overview

G protein subunit gamma 10 pseudogene 1 (GNG10P1) is a pseudogene related to the G protein gamma (γ) subunit family. Unlike active G protein subunit gamma genes, which encode critical components of the heterotrimeric G protein complex involved in G protein-coupled receptor (GPCR) signaling, GNG10P1 does not produce a functional protein and has no known biological activity in signal transduction or relevance as a therapeutic target[3][5]. It may exist as a genomic remnant without coding capacity or established functional significance. The G protein gamma subunit family (e.g., GNG10) plays roles in GPCR signaling, but this is only for the protein-coding genes[1][3][5]. The designation "pseudogene" means GNG10P1 is a genomic DNA sequence similar to a functional gene but typically non-functional due to mutations, lack of expression, or other reasons; thus, it is not classified among receptors, enzymes, or transporters and is not a therapeutic target[2][3][5]. If you are interested in the biologically relevant, protein-coding member, refer to "G protein subunit gamma 10" (GNG10), which is an actual gamma subunit of the G protein complex with roles in GPCR-mediated signal transduction[3][5]. However, "GNG10P1" specifically refers to a pseudogene and is not a functional drug target.

Other names
GNG10 pseudogene 1G protein gamma 10 pseudogene 1

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