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GABA receptor-associated protein-like 2 pseudogene

Molecular classification
Other
01

Overview

GABA receptor-associated protein-like 2 pseudogene (ENSG00000254247) refers to a non-coding genomic sequence that resembles the GABARAPL2 gene but does not encode a functional protein. Pseudogenes are generally considered non-functional vestiges of genes and are not known to play direct biological roles nor to be therapeutic targets. The functional, protein-coding gene in this family is GABARAPL2, which is involved in autophagy and intracellular trafficking, but the pseudogene version (ENSG00000254247) is not active and thus lacks therapeutic or disease relevance[1][3]. This entry is not a valid therapeutic target, is not involved in any known biological function or disease process, and there is nothing to suggest drugs or biomarkers are associated with it. The correct, functional target in humans would be "GABA receptor-associated protein-like 2" (GABARAPL2), not the pseudogene[1][3].

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