GABA type A receptor associated protein like 3 pseudogene (GABARAPL3 (pseudogene))

The entry "GABA receptor-associated protein pseudogene" (ENSG00000258148) refers to a predicted human pseudogene, not an actively expressed or functional protein-coding gene. It is associated with the GABARAPL3 gene locus, which itself is a pseudogene in the context of Homo sapiens. GABA type A receptor associated protein like 3 pseudogene (GABARAPL3, ENSG00000258148) is a predicted human pseudogene homologous to genes encoding proteins in the Atg8 family (notably GABARAPL1/GABARAPL2). Like other pseudogenes, it does not encode a functional protein and has no known biological function, therapeutic relevance, or associated drug interactions in humans. Evidence points to lack of coding potential and absence of a role as a therapeutic target. GABARAPL3 is classified as a pseudogene, not a functional receptor, enzyme, or protein. There is no evidence for protein expression, biological functions, or disease associations for GABARAPL3 pseudogene in humans. The abbreviation GABARAPL3 is used for both the protein-coding (in non-human species or predicted form) and human pseudogene loci. Unlike the GABAA receptor family or Atg8 family members (e.g., GABARAP, GABARAPL1), this gene product is non-functional as per current annotations. Some predicted gene ontologies (e.g. GABA receptor binding, ubiquitin ligase binding) are based on homology but do not reflect actual biological activity in humans. This entry is NOT a therapeutic target and contains no meaningful biological or pharmacological information relevant to drug discovery or biomarkers in humans. It is best flagged as a predicted pseudogene.

Other names

ATG8D (pseudogene)GABA(A) receptors associated protein like 3 (pseudogene)