galactose-3-O-sulfotransferase 4 pseudogene (No widely used abbreviation for the pseudogene; GAL3ST4 is for the functional gene[2])

The galactose-3-O-sulfotransferase 4 pseudogene (ENSG00000274977) is a non-functional DNA sequence homologous to the GAL3ST4 gene, which encodes an enzyme that catalyzes the transfer of sulfate to galactose residues in O-linked glycoproteins[2]. Unlike the functional GAL3ST4 gene, the pseudogene does not produce an active enzyme and does not participate in known biological processes or disease mechanisms[2]. Key distinctions: - The functional GAL3ST4 gene encodes an enzyme involved in glycoprotein sulfonation, is classified as an enzyme, and has limited disease associations[1][4][7][10]. - The GAL3ST4 pseudogene (ENSG00000274977) is not a functional target, not therapeutic, and does not fulfill typical drug target criteria[2]. Summary: This entry should not be used as a canonical therapeutic target as it refers to a pseudogene, not to the active galactose-3-O-sulfotransferase 4 enzyme[2]. If seeking information for functional therapeutic targeting, refer to GAL3ST4 rather than its pseudogene.

Other names

Galactose-3-O-sulfotransferase 4 pseudogeneGAL3ST4Pvarious Ensembl/NCBI IDs

None (no mechanism as pseudogene does not produce a protein target)