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Target intelligence / Profile preview
Galactosidase beta 1 like 2 (GLB1L2)
- Target
- GLB1L2
- Molecular classification
- Enzyme, Glycosyl hydrolase family 35
01
Overview
Galactosidase beta 1 like 2 (GLB1L2) is a protein-coding gene predicted to encode an enzyme with beta-galactosidase activity, potentially acting on O-glycosyl compounds in the galactose catabolic process[3]. It belongs to the glycosyl hydrolase family 35 and shares conserved domains with related enzymes, such as GLB1 and GLB1L3[2]. GLB1L2 is predicted to be located extracellularly and possibly in the vacuole; experimental support for its precise cellular localization and physiological roles in humans is lacking[3]. While its paralogs are implicated in lysosomal storage diseases, and related pathways connect to glycosaminoglycan and sphingolipid metabolism, there is as yet no strong evidence that GLB1L2 is a direct therapeutic target, disease biomarker, or associated with specific drugs or mechanisms of action in the clinic[3][2].
- Other names
- Beta-galactosidase-1-like protein 2MSTP014UNQ210/PRO236MST114MSTP114GLB1L2
02
Biological functions
Predicted beta-galactosidase activityhydrolyzing O-glycosyl compoundsgalactose catabolic process
03
Disease associations
Other (Associational, not causative: weakly associated or predicted with GM1 gangliosidosis via related pathways but not as primary cause)[3]
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