Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Galanin Receptor (GALR)
- Target
- GALR
- Molecular classification
- G protein-coupled receptor (GPCR)
01
Overview
The galanin receptor family comprises three G protein–coupled receptor subtypes (GALR1, GALR2, and GALR3) that mediate the effects of the neuropeptide galanin. These receptors are widely expressed in the nervous system and regulate diverse physiological processes, including energy metabolism, pain modulation, and sleep homeostasis. They represent potential therapeutic targets for a range of neurological and metabolic disorders.
- Other names
- Galanin Receptor 1GALR1Galanin Receptor 2GALR2Galanin Receptor 3GALR3
02
Mechanism of action
Agonism or antagonism of galanin receptors, modulation of G protein signaling pathways.
03
Biological functions
Signal transductionEnergy metabolism regulationNeuropathic pain modulationEpileptic activity regulationSleep homeostasisNeurotransmitter release modulation
04
Disease associations
Neuropathic painEpilepsyMetabolic disordersSleep disordersDepression
05
Safety considerations
Potential for off-target effects due to GPCR promiscuityComplex and subtype-specific roles in different tissues and diseases
06
Interacting drugs
M15 (Galantide)
13 more in the full profile.
Beyond the preview
Go deeper on Galanin Receptor (GALR).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Galanin Receptor (GALR).