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Target intelligence / Profile preview
Gamma-tubulin complex component 2 (TUBGCP2)
- Target
- TUBGCP2
- Molecular classification
- Other (component of gamma-tubulin ring complex, microtubule nucleation factor)
01
Overview
Gamma-tubulin complex component 2 (TUBGCP2) is a core protein subunit of the gamma-tubulin ring complex (gTuRC), which is essential for microtubule nucleation at the centrosome in human cells. This complex serves as a template and scaffold for the assembly of microtubules, playing critical roles in organizing the microtubule cytoskeleton, as well as ensuring proper cell division and mitotic spindle formation.
- Other names
- GCP2GCP-2hGCP2h103phGrip103hSpc97Spc97pSPBC97ALP4Gamma-ring complex protein 103 kDaSpindle pole body protein Spc97 homologtubulin gamma complex associated protein 2
02
Biological functions
Microtubule nucleationRegulation of cell divisionOrganization of microtubules at centrosomes
03
Disease associations
Other (No well-established disease roles; limited association with rare genetic syndromes implied in some studies, but not majorly linked to cancer, inflammation, etc.)
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