Target intelligence / Profile preview

Gastric fundus vasculature

01

Overview

The "gastric fundus vasculature" describes the arterial and venous blood vessels that supply the fundus, the dome-shaped upper portion of the stomach. Major arteries supplying the fundus include the short gastric arteries (branches of the splenic artery), the left gastric artery, the left gastroepiploic artery, and sometimes accessory branches from other arteries[1][2][3][6]. These vessels are essential for maintaining tissue viability and function in the fundic region and have clinical importance during gastric surgery or in the setting of upper gastrointestinal bleeding. This entry is not a molecular or druggable target but rather a vascular anatomical entity. For drug discovery, focus should be redirected to specific molecular components (such as receptors or ion channels expressed in the fundic vasculature, if relevant).

Other names
Fundic branches of the stomachFundic arteriesGastric fundus blood vesselsShort gastric arteries
02

Mechanism of action

Not applicable; no ligand or direct molecular modulation

03

Biological functions

Blood supply to the gastric fundusOxygen and nutrient delivery to gastric tissuesRemoval of metabolic waste from the gastric fundus
04

Disease associations

Upper gastrointestinal bleeding (when eroded or injured)Peptic ulcer disease (as a bleeding source)Surgical landmark in some resections (can be relevant to gastric cancer surgery)
05

Safety considerations

Risk of severe bleeding during surgical procedures involving the gastric fundusPotential for ischemia if main vessels are occluded or inadvertently ligated
06

Interacting drugs

Vasopressors (affect vascular tone, but not a molecular interaction with the vessels themselves)

1 more in the full profile.

Beyond the preview

Go deeper on Gastric fundus vasculature.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Gastric fundus vasculature.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call