Target intelligence / Profile preview

Gastric Acid (None)

Target: None
Molecular classification: Mixture/Secretion

Overview

Gastric acid, also known as stomach acid, is a highly acidic fluid produced by the parietal cells in the gastric glands of the stomach lining. Its primary component is hydrochloric acid (HCl), and it plays a crucial role in digestion, nutrient absorption, and defense against pathogens. It is not a target itself but rather its secretion can be modulated by drugs.

Other names: Stomach AcidGastric Juice

Mechanism of action

N/A (Gastric acid is a naturally produced secretion, not a drug target itself. Drugs affect its production or neutralize it.)

Biological functions

DigestionNutrient AbsorptionAntimicrobial Defense

Disease associations

Gastrointestinal Infections (decreased acidity)Anemia (impaired nutrient absorption)Mineral Imbalances (impaired nutrient absorption)

Safety considerations

Increased risk of gastrointestinal infections with reduced acidityNutrient malabsorption with prolonged acid suppressionIncreased risk of gastric cancer with long-term PPI use (controversial)

Interacting drugs

Proton Pump Inhibitors (PPIs)

2 more in the full profile.

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