Target intelligence / Profile preview

Gastric Lipase and Pancreatic Lipase (LIPF (for Gastric Lipase), PNLIP (for Pancreatic Lipase))

Target: LIPF (for Gastric Lipase), PNLIP (for Pancreatic Lipase)
Molecular classification: Enzyme, Alpha/beta-hydrolase fold superfamily, Serine hydrolases

Overview

Other names: Gastric lipase: LIPF, acid-stable lipolytic enzymePancreatic lipase: PNLIP, triacylglycerol hydrolaseLingual lipase (related acidic lipases)Acidic/alkaline lipases (context-dependent)Orlistat target enzymes

Biological functions

Triglyceride hydrolysis (breaks down dietary fats into free fatty acids and glycerol/monoacylglycerols)Lipid digestion and absorption in the gastrointestinal tractFat metabolism regulationEssential for dietary fat processing in neonates and adults[1][5][7]

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