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GC-rich promoter binding protein 1-like 1 pseudogene

Molecular classification: Pseudogene, Non-coding RNA locus (if transcribed)

Overview

The GC-rich promoter binding protein 1-like 1 pseudogene (ENSG00000250200) is a non-functional genomic region highly homologous to the GPBP1L1 gene. Like other pseudogenes, it originated via duplication or retrotransposition and contains disabling mutations that prevent the production of a functional protein[2][5][6]. While pseudogenes may be transcribed and contribute non-coding RNAs with potential epigenetic or regulatory functions, most remain biologically silent. No therapeutic interventions or drug mechanisms are relevant for this locus[10]. This pseudogene is related to the parent GPBP1L1 gene, which is predicted to be involved in DNA and RNA binding and transcriptional regulation, but this pseudogene itself does not encode any active protein[10][1][7].

Other names: GPBP1L1 pseudogeneGC-rich promoter binding protein 1-like 1 pseudogeneGPBP1L1P

Mechanism of action

None. Drugs do not act directly on pseudogenes.

Biological functions

Pseudogenes may occasionally yield non-coding RNAs that regulate gene networks by acting as competing endogenous RNAs or generating small RNAs that influence chromatin structure and gene expression, but there are no specific biological functions described for this pseudogene

Disease associations

The general role of pseudogenes in disease remains under study, but this specific pseudogene is not directly implicated in any disease processes

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