GCSH pseudogene 3 (GCSHP3)

GCSH pseudogene 3 (GCSHP3) is a non-protein-coding genomic locus related to the Glycine cleavage system protein H (GCSH). Pseudogenes are defined by their resemblance to a parent gene but contain disabling mutations that prevent them from encoding functional proteins. GCSHP3 is not involved in glycine cleavage or metabolic pathways directly, nor does it play a functional role in cell signaling, drug response, or disease. Instead, like other pseudogenes, it may contribute to genomic architecture and occasionally to regulatory phenomena, but its presence can pose challenges for genomic data analysis due to its high sequence similarity to protein-coding genes. There is no evidence it acts as a receptor, enzyme, transporter, or transcription factor, nor is it validated as a clinical biomarker or therapeutic target.

Other names

GCSHP3Glycine cleavage system H pseudogene 3