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Gene Transference
- Molecular classification
- Biological Process, Technology
01
Overview
Gene transference, also known as gene transfer, is the process of introducing new genetic material (DNA or RNA) into an organism’s cells. This can occur naturally or be performed artificially for research or therapeutic purposes. It involves mechanisms like transformation, transduction, and conjugation, as well as technologies like CRISPR-Cas systems, electroporation, and viral vectors. Its clinical applications include gene therapy for correcting defective genes, providing new functions (e.g., cancer immunotherapy), or marking cells for tracking during treatment development. It is a technology and biological process, not a direct therapeutic target like a receptor or enzyme.
- Other names
- Gene TransferHorizontal Gene Transfer (HGT)Vertical Gene Transfer
02
Biological functions
Genetic modificationGene deliveryIntroduction of new genetic materialHorizontal Gene TransferVertical Gene TransferGenome Editing
03
Disease associations
Gene therapy for genetic diseasesCancer immunotherapy (indirectly, through cell modification)Treatment development (cell tracking)
04
Safety considerations
Off-target effectsUnintended consequencesPotential risks in clinical applications
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