General metabolism pathway

General metabolism pathways" is not a specific molecule or therapeutic target but rather refers to the collective network of interconnected biochemical reactions that occur within cells to sustain life. These include both **catabolic** (breaking down molecules for energy) and **anabolic** (building complex molecules from simpler ones) processes[3][5][6]. Key examples are glycolysis, citric acid cycle (Krebs cycle), electron transport chain/oxidative phosphorylation, gluconeogenesis, glycogen synthesis and breakdown, fatty acid synthesis and oxidation, pentose phosphate pathway, urea cycle, amino acid metabolism, cholesterol biosynthesis, and nucleotide metabolism[1][4][7]. Metabolism as a whole is essential for converting nutrients into energy (ATP), synthesizing necessary cellular components like proteins and nucleic acids, maintaining blood glucose levels through liver function and hormonal regulation (e.g., insulin/glucagon), detoxifying ammonia via the urea cycle in the liver[2][4], and adapting to fasting or feeding states. Because "general metabolism pathways" does not refer to a single protein or defined molecular entity but rather an entire class of biological processes involving many enzymes and regulatory factors[3][5], it cannot be considered a druggable target in itself. Instead individual enzymes or regulators within these pathways—such as hexokinase in glycolysis or carnitine acyltransferase in fatty acid oxidation—are sometimes targeted therapeutically. In summary: > "General metabolism pathways" describes broad sets of chemical reactions fundamental to cell survival; it is not a specific receptor/protein/enzyme/transporter suitable for direct drug targeting. Therefore this entry should be flagged as incorrect if used as a molecular target name[3][5].

Other names

General metabolic pathwayMetabolic pathwaysMajor metabolic pathways