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General microbial targets affected by Cynodon dactylon extracts refers to a broad range of pathogenic bacteria and fungi susceptible to the bioactive compounds found in Bermuda grass. These extracts, typically prepared using water, ethanol, or methanol, contain secondary metabolites such as flavonoids, alkaloids, and tannins that exhibit significant antimicrobial properties (Nagori & Solanki, 2011). The primary biological function involves the inhibition of microbial growth by targeting structural components like the cell wall or interfering with vital metabolic and biosynthetic pathways (Duraipandiyan et al., 2006). In the context of disease, these targets are relevant to treating various infections, including those caused by Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa (Kaur et al., 2011). While Cynodon dactylon has a long history in traditional medicine for its antiseptic and anti-inflammatory properties, it is not a single molecular target but rather a collective term for the various microbial entities and processes impacted by the plant's complex chemical profile (Savadogo et al., 2004).
The extracts exert antimicrobial effects through the synergistic action of phytochemicals such as flavonoids, tannins, and alkaloids, which disrupt microbial cell membranes, inhibit essential enzymes, and interfere with protein synthesis (Kaur et al., 2011; Nagori & Solanki, 2011).
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