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The term "General proteins" refers to a broad and non-specific category of biological macromolecules rather than a single, well-defined therapeutic target. Proteins are essential components of all living organisms, participating in virtually every cellular process, including enzymatic catalysis, signal transduction, and structural support (UniProt Consortium, 2023). In pharmacology and drug discovery, a target is typically a specific protein, such as a receptor or enzyme, that can be modulated by a drug to achieve a therapeutic effect (Santos et al., 2017). Because "General proteins" encompasses an immense variety of molecules with distinct structures and functions, it lacks the specificity required for drug development. Consequently, this term is considered an incorrect or overly broad designation for a target, as therapeutic intervention requires the identification of a specific molecular entity (Alberts et al., 2017). Identifying a specific protein within this category is necessary for meaningful therapeutic development and safety assessment.
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