general transcription factor IIIA pseudogene 2 (GTF3AP2)

General transcription factor IIIA pseudogene 2 (GTF3AP2) is a human gene classified as a pseudogene, meaning it does not encode a functional protein product. It is named for its genomic similarity to the general transcription factor IIIA (GTF3A) gene, but unlike GTF3A, GTF3AP2 is not expressed as a functional protein and its biological role, if any, remains unclear[7][8]. Pseudogenes can sometimes be transcribed, but they do not typically produce functional proteins, and their relevance as therapeutic or diagnostic targets is very limited. There are no known associated diseases, molecular interactions, or clinical applications for GTF3AP2. Some sources mention possible regulatory RNA effects in specific contexts, such as erythroid differentiation, but there is currently no recognized disease implication or drug interaction[6]. The gene is located on chromosome 14 (positions 71,044,375-71,044,640, reverse strand)[7]. This is not considered a therapeutic target (e.g., receptor, enzyme, transporter) and should not be included as such. The name and abbreviation are correct, but it is a pseudogene, thus generally excluded from lists of actionable drug targets. There is no evidence for function, disease relevance, or druggability in current biomedical literature[7][8][6].

Other names

GTF3AP2general transcription factor IIIA pseudogene 2