Genetic modification via nucleic acid introduction

Genetic modification via nucleic acid introduction refers to the process of altering an organism’s genetic material by physically introducing DNA or RNA into cells. This can involve methods such as recombinant DNA, gene editing (e.g., CRISPR-Cas9), viral vector delivery, or plasmid transfection[1][2][5]. The process is widely used in research, agriculture, and medicine to create genetically modified organisms, correct genetic diseases (gene therapy), produce therapeutic proteins, or study gene function. It does not define a unique molecular entity, but rather a family of biotechnological methods.

Other names

Genetic engineeringgene editingrecombinant DNA technologyDNA modification

Introduction of foreign or modified nucleic acids to change cellular function or phenotype Repair, removal, or addition of genetic material via techniques like CRISPR-Cas9, plasmid transformation, viral transduction, or gene targeting