Target intelligence / Profile preview

Germ cell-specific gene 1-like protein 2 (GSG1L2)

Target
GSG1L2
Molecular classification
Other (protein with predicted plasma membrane localization; not a receptor, enzyme, transporter, or well-defined ion channel as of current annotation)
01

Overview

Germ cell-specific gene 1-like protein 2 (GSG1L2) is a protein-coding gene located on human chromosome 17p13.1. The protein is predicted to localize to the plasma membrane but its precise molecular function remains uncharacterized as of current knowledge. It is a paralog of GSG1L, which is implicated in AMPA receptor modulation, but GSG1L2 itself has not been directly linked to such receptor or channel activity. Disease annotations exist for rare syndromic disorders, though its mechanistic role is undefined. There are currently no reported drugs, clinical biomarkers, or specific therapeutic safety concerns for this protein. GSG1L2 is best classified as a putative or uncharacterized membrane protein with unknown function and no demonstrated therapeutic target relevance.

Other names
GSG1 like 2GSG1L2GSG1-like protein 2germ cell-specific gene 1-like protein 2germ cell-specific gene 1-like protein 2-likeputative germ cell-specific gene 1-like protein 2
02

Biological functions

Unknown/Other (predicted membrane protein, specific biological function not characterized as of current annotation)
03

Disease associations

Other (reported association with rare Mendelian disorders such as hypogonadotropic hypogonadism type 15 with or without anosmia and Sifrim-Hitz-Weiss syndrome)

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