Target intelligence / Profile preview

GIMAP family P-loop NTPase domain containing 1 (GIMD1)

Target
GIMD1
Molecular classification
Other, P-loop NTPase superfamily, GTPase
01

Overview

GIMAP family P-loop NTPase domain containing 1 (GIMD1) is a predicted protein-coding gene identified in humans and mice, related to the GIMAP family of GTPases, which are believed to play roles in immune cell development and survival. However, there is a lack of direct experimental evidence for its biological function, disease associations, or roles as a therapeutic target. No specific drugs or mechanisms of action have been described for this protein, and it is not established as a canonical therapeutic target[1][2][4][5][6][7][8]. Key notes regarding this entry: - GIMD1 does not have confirmed activity as a therapeutic target, receptor, enzyme, or transporter, nor experimental validation for key biological functions. - It is included in large gene annotation databases, but most information is predicted or inferred, so caution should be taken when using it as a formal target or biomarker[2][4][6]. - The entry is most appropriately classified as a gene of unknown specific function in the GIMAP/P-loop NTPase family, rather than an established receptor or enzyme[2][4][6]. Summary: This is a predicted, unvalidated gene product in the GIMAP P-loop NTPase superfamily, with no established role as a therapeutic target. It should not be used as a canonical receptor or druggable target entry at this time.

Other names
GTPase IMAP family member GIMD1GIMAP family P-loop NTPase domain-containing protein 1GIMD1LOC108706726Gm5549
02

Biological functions

GTP binding (predicted)possibly involved in immune system regulation (inferred from GIMAP family role)
03

Disease associations

Human cytomegalovirus infection (potential association)

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