GLI family zinc finger 4 (GLI4)

GLI family zinc finger 4 (GLI4) encodes a predicted transcription factor that contains zinc finger domains and is thought to regulate nuclear DNA-templated transcription by binding gene promoters in a sequence-specific manner, acting primarily through RNA polymerase II. It is located on chromosome 8. The gene shares similarity with other zinc finger proteins and is annotated in gene and protein databases by multiple aliases. GLI4 is associated in the literature with regulation of gene expression but remains poorly characterized, with no direct links to drug therapies, biomarkers, or targeted safety literature. *Note: The molecular and disease information is fragmentary; there is no authoritative evidence establishing GLI4 as a direct therapeutic target, nor known drugs acting on it. Many listed aliases are redundant or alternative database names rather than distinct protein forms.

Other names

GLI4HKR4ZNF928Zinc finger protein GLI4Protein HKR4Krueppel-related zinc finger protein 4GLI-Kruppel family member GLI4Glioma-associated oncogene family zinc finger 4

None established; no drugs targeting GLI4, so no mechanisms set