Target intelligence / Profile preview

Glial Cell Function

Molecular classification: Other

Overview

Glial cell function encompasses a broad range of activities vital to nervous system health—including physical support for neurons, regulation of chemical environments necessary for signaling, immune defense within neural tissues, formation/maintenance of myelin sheaths around axons both centrally and peripherally—and their dysfunction contributes significantly to neurological disease pathology.

Biological functions

Structural support of neuronsRegulation of neurotransmissionMaintenance of extracellular ion balanceMyelination of axonsGuidance of neuron developmentRepair processes after injuryFormation of the blood-brain barrierModulation of synaptic communication and plasticityImmune defenseRegulation of blood flowEnergy storageHomeostasisMetabolismGut motility

Disease associations

Neurodegenerative disordersNeurotraumaNeuropathiesBrain tumors (gliomas)Inflammatory conditionsSpinal cord injury

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