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GLIS3 antisense RNA 1 (GLIS3-AS1)
- Target
- GLIS3-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA
01
Overview
GLIS3 antisense RNA 1 (GLIS3-AS1) is a long non-protein coding RNA that acts in an antisense orientation to the GLIS3 gene. It is known to interact with the promoter region of GLIS3 and may negatively regulate GLIS3 gene expression by interfering with transcription. Such antisense RNAs generally modulate gene expression through mechanisms like promoter competition, transcriptional interference, or chromatin modification, impacting their corresponding sense genes’ transcription and cellular functions. GLIS3-AS1 has aliases including C9orf70 and MGC16153, and is registered under NCBI Gene ID 84850 and Ensembl ENSG00000237009.
- Other names
- C9orf70MGC16153GLIS3-AS1GLIS3 antisense RNA 1 (non-protein coding)
02
Biological functions
Negative regulation of gene expression (targets the promoter region of GLIS3 and negatively regulates its transcription)Antisense RNA-mediated regulation of gene expression
03
Disease associations
Other (potential association inferred from regulation of GLIS3, but no direct disease links are established for GLIS3-AS1 itself; GLIS3 is related to organ development and disease)
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