Target intelligence / Profile preview

Globo H glycosphingolipid

Molecular classification
Glycosphingolipid, Globoside, Antigen
01

Overview

Globo H glycosphingolipid is a hexasaccharide-containing globoside expressed on the surface of various cancer cells, including breast, prostate, and pancreatic cancers, but not on normal tissues. It plays roles in cell adhesion, signal transduction, and tumor progression/metastasis and is a potential target for cancer immunotherapy.

Other names
Globo Hglobohexaosylceramide
02

Biological functions

Cell adhesionSignal transductionTumor progressionMetastasis
03

Disease associations

Cancer
04

Biomarkers

Globo H expression in cancer cells

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