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Gluconate ion
- Molecular classification
- Other, Simple organic acid anion
01
Overview
The gluconate ion is an organic anion derived from gluconic acid, featuring a six-carbon chain with five hydroxyl groups and one terminal carboxylate group (-COO⁻)[4][8]. It is formed by the oxidation of glucose and is present naturally in fruits, honey, and wine[4][1]. The ion is well known for its ability to chelate metal ions such as calcium, iron, and magnesium, a property exploited in medical products and cleaning agents[5][1]. Pharmaceutical uses are mostly as salts—calcium, ferrous, or quinidine gluconate—where the cation is therapeutically active, and gluconate acts as a safe, water-soluble carrier[4]. The molecule is not itself a protein, receptor, enzyme, or biological target, but rather a metabolite and excipient.
- Other names
- D-gluconateGluconate anionGluconic acid anion2,3,4,5,6-pentahydroxyhexanoateDextronateGlycogenateGlyconateMaltonateD-gluconate ionGluconate [RXNORM]CHEBI:18391
02
Biological functions
Metabolite of glucose oxidationPharmaceutical excipientFood additiveChelation of metals (e.g., Ca²⁺, Fe²⁺)
03
Disease associations
Not implicated as a direct disease target
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