Target intelligence / Profile preview

Gluconeogenesis Pathway

Molecular classification
Metabolic Pathway
01

Overview

Gluconeogenesis is a metabolic pathway that synthesizes glucose from non-carbohydrate precursors. This process is essential for maintaining blood glucose levels during fasting, starvation, or prolonged exercise. The pathway primarily occurs in the liver and to a lesser extent in the renal cortex.

02

Mechanism of action

Regulation of glucose production

03

Biological functions

Maintains blood glucose homeostasisProvides glucose for tissues highly dependent on itComplements glycogenolysis
04

Disease associations

HypoglycemiaHyperglycemiaDiabetes
05

Safety considerations

Lactic acidosisHyperglycemia

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