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Glucose metabolism pathways, including glycolysis, the pentose phosphate pathway, and oxidative phosphorylation, play a crucial role in energy production and cellular functions. These pathways are often reprogrammed in cancer cells to support rapid proliferation and survival, making them attractive targets for cancer therapy. Drugs targeting these pathways can modulate glucose uptake and metabolism, affecting tumor growth and survival.
Inhibition of glucose uptake (e.g., SGLT2 inhibitors), modulation of glycolytic enzymes, interference with signaling pathways (e.g., Akt)
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