Glucose oxidase-based enzymatic electrochemical biosensor

An enzymatic electrochemical biosensor for interstitial glucose concentration measurement is a diagnostic device that quantifies the amount of glucose present in interstitial fluid—often via minimally invasive or noninvasive means such as microneedles or wearable patches. The core sensing element typically uses an enzyme such as glucose oxidase (GOx) or glucose dehydrogenase (GDH), which catalyzes the oxidation of glucose. This enzymatic reaction generates electrons that are detected by an electrode system through amperometric or voltammetric methods[3][6]. The resulting electrical signal correlates with local interstitial fluid glucose concentrations. These sensors have been widely adopted in continuous monitoring systems for diabetes care due to their specificity and sensitivity. Advances include miniaturization for wearable applications and improved stability through optimized enzyme immobilization techniques[1][3]. While highly effective as analytical tools, these devices are not themselves therapeutic targets but rather platforms enabling real-time biochemical monitoring. The term provided ("Interstitial glucose concentration measurement via enzymatic electrochemical biosensor") refers to a measurement method rather than a specific molecule/receptor/therapeutic target. Therefore: This entry does not correspond to a canonical molecular target, but instead describes an analytical technology/device based on enzymes like GOx[6]. If you require structured information about the actual biological molecule involved in these sensors—such as "Glucose oxidase"—that can be provided separately.

Other names

Enzymatic glucose biosensorElectrochemical glucose sensorGlucose oxidase sensorGOx-based biosensor