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Glucuronidase beta pseudogene 2 (GUSBP2)

Target: GUSBP2
Molecular classification: Other (pseudogene)

Overview

Glucuronidase beta pseudogene 2 (GUSBP2) is a pseudogene located on human chromosome 12[1][3][5]. Unlike its parent gene GUSB, which encodes the lysosomal enzyme beta-glucuronidase, GUSBP2 does not code for a functional protein and is not known to have any enzymatic activity or protein product[3][5]. It is highly expressed in the brain, which suggests possible roles in neuronal gene regulation, but no confirmed biological function or pathological association is established[1]. GUSBP2 is not considered a therapeutic target, and no drugs or biomarker associations are reported for this locus[1][3][5].

Other names: bA239L20.5bA239L20.1SMA3-LbGLU-LpSMAC3Lglucuronidase, beta pseudogene 2spinal muscular atrophy candidate gene 3-like 2glucuronidase beta-like 1

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