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Glutamate dehydrogenase 1 pseudogene 5 (ENSG00000231855) is annotated as a **pseudogene** related to the functional glutamate dehydrogenase genes (such as GLUD1 and GLUD2) but does **not encode a functional enzyme or protein**[1][3][4]. Pseudogenes typically arise through duplication or retrotransposition followed by accumulation of mutations rendering them nonfunctional. This locus does not mediate glutamate metabolism, does not produce a protein, and is not considered a drug target or biomarker. Functional glutamate dehydrogenase enzymes are crucial for amino acid and energy metabolism, but the pseudogene itself does not participate in these processes[3][4][5]. No clinical, biological, or pharmacological relevance is attributed to glutamate dehydrogenase 1 pseudogene 5. *For structured target-centric analyses and databases, omit this entity from therapeutic target lists, and do not use it for profiling or selection in drug discovery pipelines.*
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