Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Glutamate-rich protein 6 (ERICH6)
- Target
- ERICH6
- Molecular classification
- Other (protein coding gene, not a member of canonical receptor/enzyme/transporter families)
01
Overview
Glutamate-rich protein 6 (ERICH6) is a nuclear protein encoded by the ERICH6 gene, located on chromosome 3. It is expressed selectively in spermatogonia in the testis and is associated by annotation with certain neurological disorders, such as Giant Axonal Neuropathy 2 and Pyruvate Dehydrogenase E1-Alpha Deficiency[3][7]. The biological function of ERICH6 remains largely uncharacterized, though recent evidence suggests its antisense transcript (ERICH6.AS1) may play a role in modulating immune responses and serve as a prognostic biomarker in cancers such as cervical squamous cell carcinoma[1].
- Other names
- FAM194AC3orf44ERICH6AMGC39662Glutamate-rich protein 6AProtein FAM194AFamily with sequence similarity 194, member A
02
Biological functions
Selective cytoplasmic expression in spermatogonia in testisMay be involved in immune regulatory pathways (based on its antisense transcript, ERICH6.AS1, function in tumor immune microenvironment modulation)General protein function is not well characterized
03
Disease associations
Has been associated with Giant Axonal Neuropathy 2Pyruvate Dehydrogenase E1-Alpha DeficiencyPotential prognostic biomarker and therapeutic role in cervical squamous cell carcinoma via its antisense transcript ERICH6.AS1
04
Biomarkers
ERICH6.AS1 may serve as a prognostic biomarker in cervical squamous cell carcinoma
Beyond the preview
Go deeper on Glutamate-rich protein 6 (ERICH6).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Glutamate-rich protein 6 (ERICH6).