Glutamic-oxaloacetic transaminase 2 pseudogene 1 (GOT2P1)

Glutamic-oxaloacetic transaminase 2 pseudogene 1 (GOT2P1) is classified as a pseudogene, meaning it is a genomic DNA sequence similar to a normal gene but typically non-functional; it does not encode a biologically active protein and is not expected to possess enzymatic or signaling function. While the protein-coding gene GOT2 plays a critical role in amino acid metabolism and mitochondrial function, GOT2P1 represents only a related, non-coding, and likely non-functional genomic element; consequently, GOT2P1 is not considered a therapeutic target, has no established biological function, and is not associated with human disease or drug interactions. **Supporting details and clarification:** - **Canonical name standardization**: The consistently used scientific name for this pseudogene is "Glutamic-oxaloacetic transaminase 2 pseudogene 1". - **Is this a therapeutic target?** Pseudogenes lack the biological activity, ligand-binding capacity, or enzyme function required to be "targets" in drug discovery or therapy. - **Aliases**: Multiple names listed are all variants or descriptors of the same pseudogene (e.g., GOT2 pseudogene 1, GOT2L1, etc.). - **Biological and disease roles**: No documented or established biological function or implication in disease for this pseudogene. It is annotated as a pseudogene and not experimentally linked to pathophysiology. - **No drugs or mechanism of action, biomarker potential, or safety considerations** are relevant for this pseudogene. - **Related information**: The functional enzyme is encoded by the GOT2 gene, not by this pseudogene. **Summary**: Glutamic-oxaloacetic transaminase 2 pseudogene 1 (GOT2P1) is a non-coding genomic sequence resembling the functional GOT2 enzyme gene but lacks protein-coding and functional activity. It is not considered a therapeutic target, has no proven biological function, and is not involved in disease or drug response.

Other names

GOT2 pseudogene 1Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) pseudogeneGOT2L1Glutamic-oxaloacetic transaminase 2-like 1 pseudogeneGOT2 Pseudogene 1