Target intelligence / Profile preview

Glutamic-oxaloacetic transaminase 2 pseudogene 5 (GOT2P5)

Target
GOT2P5
Molecular classification
Other (Pseudogene)
01

Overview

GOT2 pseudogene 5 (GOT2P5) is a non-functional genomic locus related by sequence to the glutamic-oxaloacetic transaminase 2 gene. Unlike functional protein-coding genes, pseudogenes typically lack protein output due to disabling mutations. GOT2P5 does not encode a functional enzyme and has no confirmed role in cellular biology or disease. Distinction must be made from the active mitochondrial enzyme GOT2, which participates in cellular redox balance and is implicated in cancer metabolism. The confusion often arises in literature and databases that group pseudogenes with their functional counterparts, but available evidence does not support a role for GOT2P5 in biology, disease, or as a drug target[3][4].

Other names
GOT2P5GOT2Yglutamic-oxaloacetic transaminase 2 pseudogene 5
02

Mechanism of action

None. No mechanisms of action relevant to drugs, as this pseudogene does not encode a functional target.

03

Biological functions

Other
04

Disease associations

Other

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