Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial (GATD3B)

Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial (GATD3B) is a predicted mitochondrial protein encoded by the GATD3B gene (Ensembl: ENSG00000280071), located on human chromosome 21. It belongs to the putative glutamine amidotransferase-like class 1 domain-containing protein family, showing paralogy with GATD3 (which has been studied in the context of Down syndrome), but the biological function, enzymatic activity, and disease roles of GATD3B itself remain largely uncharacterized. There is minimal evidence for its role as a therapeutic target, no established drug interactions, mechanisms of action, or biomarker roles, and no specific safety concerns are reported in the available literature.

Other names

LOC102724023Putative glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrialNovel protein, similar to chromosome 21 open reading frame 33 C21orf33ES1 protein homolog, mitochondrialProtein GT335Protein HES1Keio novel protein I (KNP-I, KNPI)Chromosome 21 open reading frame 33C21orf33