Glutaredoxin 3 pseudogene 1 (GLRX3P1)

Glutaredoxin 3 pseudogene 1 (GLRX3P1) is located on chromosome 9 (genomic location chr9:19967239-19967994 in hg38 reference). It is a noncoding genomic locus derived from the functional GLRX3 gene, which encodes a cytosolic oxidoreductase involved in iron-sulfur cluster biogenesis and regulation of apoptosis and cardiac hypertrophy. The pseudogene is not transcribed into a functional protein and does not participate in the redox, catalytic, or signaling functions attributed to glutaredoxins. Although functional glutaredoxin 3 (GLRX3) is associated with several biological processes and disease states, GLRX3P1 does not share these roles and is not recognized as a molecular target in drug discovery or clinical biomarker research. If you seek a functional target related to glutaredoxin 3, you should refer to the protein-coding gene GLRX3 rather than GLRX3P1. Any pharmacological or biological discussion of "GLRX3P1" as a target is inaccurate given current genomic and biomedical knowledge.

Other names

glutaredoxin 3 pseudogene 1GLRX3P1ENSG00000277711NCBI Gene 100418908

None. There are no mechanisms of action possible due to lack of a protein product.