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Target intelligence / Profile preview
Glutathione S-transferase alpha pseudogene 2 (GSTAP2)
- Target
- GSTAP2
- Molecular classification
- Pseudogene, Related to "Enzyme" (by sequence and family association, but not functionally)
01
Overview
Glutathione S-transferase alpha pseudogene 2 (GSTAP2; also called GSTA10P) is a member of the GST alpha family pseudogenes in the human genome[3][5]. Unlike functional GST alpha enzymes, which play significant roles in detoxification and defense against stress, pseudogenes like GSTAP2 do not produce active protein products. They are retained in the genome as evolutionary relics and are generally not expressed or involved in known cellular functions. GSTAP2 should not be considered a therapeutic target.
- Other names
- GSTAP2 (most accurate/high-confidence alias)Glutathione S-transferase alpha 10, pseudogeneGSTA10P
02
Mechanism of action
Not applicable (no therapeutic targeting or known role)
03
Biological functions
None (as a pseudogene, it is not known to have biological function)
04
Disease associations
None reported directly; pseudogenes can sometimes regulate expression of related genes via RNA interference or other mechanisms, but GSTA10P/GSTAP2 does not have reported disease associations[3][5].
05
Safety considerations
None reported; pseudogenes are not targeted therapeutically
06
Interacting drugs
None; there are no drugs that target GSTA10P/GSTAP2
07
Biomarkers
None identified
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