Glutathione S-transferase pi 1 pseudogene 1 (GSTP1P1)

GSTP1P1 encodes a non-protein-coding RNA classified as a pseudogene, closely related to the functional glutathione S-transferase pi 1 gene (GSTP1). While GSTP1 codes for a detoxification enzyme, GSTP1P1 does not code for a protein but may influence cancer progression through RNA-mediated mechanisms such as acting as a lncRNA (e.g., Lnc712) that can affect tumorigenesis by modulating microRNA pathways. GSTP1P1 is not a protein-coding gene and is not a classical molecular target for drugs (unlike GSTP1, which encodes a functional enzyme with known drug interactions). There is potential functional significance for the transcript as a lncRNA with regulatory properties in cancer but it is not a direct therapeutic target. If you are seeking information about the enzyme responsible for glutathione conjugation, the relevant gene is Glutathione S-transferase pi 1 (GSTP1), not GSTP1P1. GSTP1P1 is a pseudogene/lncRNA, not a classical drug target, and should not be confused with the functional enzyme GSTP1. If therapeutic relevance is needed, refer to GSTP1, not GSTP1P1.

Other names

GSTP1PLnc712GST3LGSTPLGSTPP