Glutathione S-transferase pseudogene

Glutathione S-transferase pseudogene (ENSG00000227878, LOC100420572) refers to a non-functional genomic element homologous to the glutathione S-transferase family, notably associated with the GST theta-class gene cluster. The corresponding pseudogene has a splice site abnormality and a premature stop codon, preventing the production of a functional enzyme[3][4]. Unlike functional GST enzymes—which catalyze glutathione-dependent detoxification reactions—this pseudogene does not encode a protein, is not expressed, and lacks any known role in normal physiology or disease. It does not participate in cellular detoxification or serve any known therapeutic function. The information above applies specifically to glutathione S-transferase pseudogenes such as GSTT2P, and does not refer to active GST proteins, many of which are important in xenobiotic metabolism[1][4].

Other names

LOC100420572ENSG00000227878Glutathione S-transferase pseudogeneGST-T2P

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