Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Glutathione S-transferase theta-2 pseudogene (GSTT2P)
- Target
- GSTT2P
- Molecular classification
- Pseudogene, Member of the glutathione S-transferase (GST) superfamily
01
Overview
Glutathione S-transferase theta-2 pseudogene (GSTT2P) is a duplicated, non-functional segment found near the functional GSTT2 gene in humans. Sequence analysis shows splice site abnormalities and a premature stop codon, preventing translation into a functional protein. GSTT2P shares sequence homology with other theta-class GSTs but has no known physiological or pathological roles, unlike the functional homologs which are involved in Phase II detoxification and potentially in carcinogenesis. GSTT2P (ENSG00000250470) is a pseudogene of the glutathione S-transferase theta family, and is not considered a therapeutic target. For valid GST theta targets, refer to GSTT1 or GSTT2.
- Other names
- GSTT2PGlutathione S-transferase theta-2 pseudogeneGST theta pseudogene
02
Mechanism of action
Not applicable (GSTT2P does not produce a protein and has no known activity)
03
Biological functions
None (as a pseudogene, it does not encode a functional protein)
04
Disease associations
None directly established; functional GST theta genes have roles in carcinogenesis and detoxification, but the pseudogene itself is not implicated in disease
05
Safety considerations
None specific (not a therapeutic target)
06
Interacting drugs
None (no known drugs interact with GSTT2P, since it is not expressed)
07
Biomarkers
None (not used as a biomarker; functional GSTT genes may be, but not the pseudogene)
Beyond the preview
Go deeper on Glutathione S-transferase theta-2 pseudogene (GSTT2P).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Glutathione S-transferase theta-2 pseudogene (GSTT2P).