Gluten Peptide Antigens (None)

Gluten peptide antigens are specific fragments of gluten proteins that trigger immune responses, particularly in individuals with celiac disease (CeD) and other gluten-related disorders. The most well-characterized immunogenic fragment is the 33-mer peptide from α-gliadin. These peptides can elicit both innate and adaptive immune responses, primarily through activation of CD4+ T cells via HLA-DQ2/DQ8 presentation. Detection of these peptides can be used to monitor dietary adherence in celiac patients. High proline and glutamine content makes these peptides resistant to digestion.

Other names

Gliadin peptidesHordein peptidesSecalin peptidesα-Gliadin 33-merDeamidated gluten peptides

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