Glyceraldehyde-3-phosphate dehydrogenase pseudogene 1 (GAPDHP1)

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 1 (GAPDHP1) is a **pseudogene** derived from the gene encoding glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a key glycolytic enzyme[4][3]. Pseudogenes are DNA sequences similar to known genes but typically nonfunctional due to mutations or lack of regulatory elements[3]. GAPDHP1 may be transcribed but generally does not encode a functional protein. While some GAPDH pseudogenes have shown evidence of rare peptide products, there is currently no strong evidence for regular translation or established biological or disease roles for GAPDHP1 specifically[1][3]. It is not considered a therapeutic target, receptor, enzyme, or transporter. Key facts: - The **canonical full name** is "Glyceraldehyde-3-phosphate dehydrogenase pseudogene 1"[4]. - **GAPDHP1** is a widely accepted abbreviation[4]. - Historically, alternative symbols include GAPDP1, GAPDHL2, GAPDL2[4]. - GAPDHP1 is classified as a **processed pseudogene** formed via retrotransposition[3]. - It is not an enzyme, receptor, or drug target, and has no established role in disease or therapeutic intervention[3][4]. - No interacting drugs, biomarkers, mechanisms of action, or safety concerns are reported for GAPDHP1. GapdHP1 is frequently catalogued in gene expression atlases but is functionless at the protein level and serves primarily as a marker for studying gene and pseudogene evolution[3][4].

Other names

GAPDP1GAPDHL2GAPDL2