Glyceraldehyde-3-phosphate dehydrogenase pseudogene 16 (GAPDHP16)

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 16 (GAPDHP16) is a processed pseudogene related to the gene encoding the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). While functional GAPDH enzymes play established roles in glycolysis and a variety of cellular processes, GAPDHP16 itself does not encode a functional protein and has no demonstrated biological function or implication as a therapeutic drug target. GAPDH pseudogenes are common in the human genome and are primarily the result of retrotransposition events. They serve as molecular records of gene evolution but are not implicated in disease, drug targeting, or biomarker utility[2][4]. Additional context: - GAPDHP16 is not a protein-coding gene, but a non-functional genomic sequence with similarity to GAPDH, and is one of many GAPDH-related pseudogenes in the human genome[2][4]. - The existence of numerous processed GAPDH pseudogenes reflects the evolutionary activity and non-glycolytic functions of the parent gene but is not associated with therapeutic interest or disease relevance[4]. - Information listed under GAPDH (the functional gene/enzyme) such as biological functions, mechanisms, and associated drugs, does not apply to GAPDHP16 as it is a pseudogene and not a therapeutic target.

Other names

GAPDP16GAPDHP16