Target intelligence / Profile preview

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 25 (GAPDHP25)

Target
GAPDHP25
Molecular classification
Other (Pseudogene)
01

Overview

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 25 (GAPDHP25) is a genomic DNA sequence in humans highly similar to the gene that encodes GAPDH, a key enzyme in glycolysis. Unlike the canonical GAPDH gene, GAPDHP25 is a *pseudogene*: a non-functional remnant of the original gene that lacks the sequence integrity or regulatory elements needed to produce a functional enzyme. The human genome contains about 25 GAPDH-related pseudogenes, many of which arose from reverse transcription and insertion events[3]. Pseudogenes such as GAPDHP25 have no known biological, pathological, or pharmacological function and are generally not considered in drug development or disease association studies[3].

Other names
GAPDH pseudogene 25Glyceraldehyde-3-phosphate dehydrogenase pseudogene 25
02

Biological functions

Other (No known biological function; non-functional gene fragment[3].)
03

Disease associations

Other (No direct disease association, as no protein is produced[3].)

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