Glyceraldehyde-3-phosphate dehydrogenase pseudogene 58 (GAPDHP58)

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 58 (GAPDHP58) is a noncoding pseudogene in the human genome, related by sequence similarity to the functional gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Pseudogenes like GAPDHP58 do not encode functional proteins and thus do not exhibit enzymatic activity or participate in known biological pathways. GAPDHP58 is one of a large family of GAPDH pseudogenes, generated by retrotransposition events over evolutionary time, and is not considered a drug target, biomarker, or disease gene[4]. Clarifications and caveats: - GAPDHP58 is a pseudogene, not a functional enzyme, receptor, or therapeutic target[4]. - Its description, molecular classification, and biological relevance should not be confused with those of GAPDH, the active glycolytic enzyme, which has broad metabolic, regulatory, and disease associations[1][2][3]. - There is no evidence of GAPDHP58 being associated with drugs, therapeutic action, or disease, nor is it used as a biomarker or associated with notable safety concerns in therapy. In summary, glyceraldehyde-3-phosphate dehydrogenase pseudogene 58 (GAPDHP58) is a non-functional pseudogene and not considered a direct molecular target for therapies or biomarker applications[4].

Other names

GAPDHL1GAPDL1Glyceraldehyde-3-phosphate dehydrogenase pseudogeneGlyceraldehyde-3-phosphate dehydrogenase-like 1 pseudogene

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