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Glyceraldehyde-3-phosphate dehydrogenase pseudogene 61 (GAPDHP61)

Target
GAPDHP61
Molecular classification
Other (Pseudogene)
01

Overview

**Glyceraldehyde-3-phosphate dehydrogenase pseudogene 61** (GAPDHP61) is a pseudogene related to the active gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) but does not encode a functional protein. This pseudogene does not have known biological function, is not classified as a therapeutic target such as enzyme or receptor, and is not linked to disease or drug interactions. Therefore, it is not a target of therapeutic or biomarker interest[1]. **Key context:** - A *pseudogene* is a non-functional copy or fragment of a gene that usually arises due to duplication or retrotransposition events and typically lacks the capacity to produce a functional protein. - There are many pseudogenes for the GAPDH gene in the genome; GAPDHP61 is one such, and the “61” indicates its enumerated order among related pseudogenes. - This entity is distinct from the functional enzyme **glyceraldehyde-3-phosphate dehydrogenase (GAPDH)**, which is an abundant, multifunctional metabolic enzyme[2][3][4]. **Summary:** GAPDHP61 is not a therapeutic target, has no known function, druggability, or biomarker role, and should not be confused with the functional gene GAPDH. If you are seeking information about the active enzyme, refer to "glyceraldehyde-3-phosphate dehydrogenase (GAPDH)" instead[1][2][3].

Other names
GAPDHP61Glyceraldehyde 3-phosphate dehydrogenase pseudogene 61

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