Glyceraldehyde-3-phosphate dehydrogenase pseudogene 62 (GAPDHP62)

Glyceraldehyde-3-phosphate dehydrogenase pseudogene 62 is a non-functional segment of DNA in the human genome that resembles the active glyceraldehyde-3-phosphate dehydrogenase gene (GAPDH), a well-characterized enzyme central to glycolysis. Pseudogenes such as GAPDHP62 arise through gene duplication or retrotransposition, but accumulate disabling mutations and are not translated into functional proteins. The existence of GAPDH pseudogenes may complicate molecular assays like quantitative PCR, but GAPDHP62 itself does not encode a functional protein, is not considered a receptor, enzyme, or therapeutic target, and has no known direct biological or clinical significance. Summary of issues: - The entity is a pseudogene, not a protein-coding gene. - It does not serve as a canonical therapeutic target or receptor. - There are no drugs or mechanisms of action associated with this pseudogene. - Existing literature typically refers to the functional GAPDH gene, not its pseudogenes, when discussing enzymes or therapeutic targets. Note: GAPDHP62 is only relevant in genomic studies, where it may impact the interpretation of results if pseudogenes are not differentiated from functional genes.

Other names

GAPDHL7GAPDL7GAPDHP62Glyceraldehyde-3-phosphate dehydrogenase-like 7, pseudogene

Not applicable