Glycerol-3-phosphate acyltransferase 2 pseudogene 1 (GPAT2P1)

Glycerol-3-phosphate acyltransferase 2 pseudogene 1 (GPAT2P1; LOC128966744) is officially classified as a pseudogene related to the functional enzyme glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT2). Pseudogenes are segments of DNA similar to known genes but are non-functional due to accumulated mutations or lack of regulatory elements required for expression. GPAT2P1 is not a functional protein, receptor, enzyme, or drug target, and there is no evidence that it is expressed or has biological or disease-related function. It should not be confused with its functional gene counterpart, GPAT2.\n\nAdditional notes and clarification:\n- GPAT2P1 is a pseudogene, which by definition means it does not encode a functional protein, and has no recognized physiological, pathological, or therapeutic role.\n- There is no evidence in the scientific literature or genome databases that GPAT2P1 is druggable or has any relevance as a therapeutic target.\n- If you intended to refer to the actively translated mitochondrial enzyme glutamate pyruvate transaminase 2 (GPT2) or to glycerol-3-phosphate acyltransferase 2 (GPAT2, a functional enzyme), those are separate and functionally active proteins, potentially confused here due to naming similarities[1][2][3]. GPAT2P1 itself is not a functional gene or protein.\n- Aliases such as \"glycerol-3-phosphate acyltransferase 2, mitochondrial\" actually refer to the functional enzyme GPAT2 (not the pseudogene), so should not be considered valid aliases for this pseudogene except for noting possible confusion.\n- For structured representation, nearly all functional and clinical fields should be null.\n\nIf you require information on the functional enzyme GPAT2 or related disease biology, please specify or clarify the target name. Currently, GPAT2P1 is not a drug target, biological regulator, or disease biomarker, and is primarily of interest in genomic annotation rather than molecular biology or medicine.

Other names

GPAT2P1glycerol-3-phosphate acyltransferase 2mitochondrialLOC128966744