Target intelligence / Profile preview

Glycerol kinase 3 (GK3)

Target
GK3
Molecular classification
Enzyme (predicted, based on homology)
01

Overview

Glycerol kinase 3 (GK3) is a protein-coding gene in humans potentially involved in the regulation of glycerol uptake and metabolism. It is a mitochondrial protein predicted to possess glycerol kinase activity and may participate in glycerol and triglyceride metabolic processes. However, GK3's function is not experimentally confirmed, and it may represent a pseudogene or a non-essential paralog. It is not considered a validated therapeutic target, and there is no evidence supporting interaction with clinical drugs, use as a biomarker, or involvement in defined safety concerns in the biomedical literature[6][7].

Other names
Glycerol kinase 3GK3GK3PGKP3GKTBGK 3Glycerokinase 3ATP:glycerol 3-phosphotransferase 3Glycerol kinase 3 pseudogeneGlycerol kinase, testis specific 1glycerol kinase pseudogene 3
02

Biological functions

Regulation of glycerol uptake and metabolism (predicted)
03

Disease associations

CysticercosisTaeniasis (associations described, but causality or mechanistic links not established)

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